Prevalence/Incidence of aneurysms: Discussion of current state of aneurysm prevalence and how it differs in different populations 3. Pathophysiology of aneurysms: Discuss the formation of aneurysms, current thinking of aneurysm development 2. Topic: Chapter discussing the indications for treatment of brain aneurysms, endovascular techniques, tips and tricks. Although these findings need to be confirmed, they may aid to improve DCI prevention and outcome predictions. Our study evidenced that patients with “O” blood type have higher risk of DCI onset after aSAH. However, there were no significant differences.
Compared to “non-O” type patients, “O” type patients had a trend to have poorer outcomes at discharge (25.5% vs. “O” type was an independent risk after in the logistic regression after adjusting for significant factors in the univariate analysis (OR=2.530, 95% CI: 1.040- 6.151, P = 0.41). About 17.9% of “O” type patients developed a DCI while DCI was reported in only 8.2% of non-O type patients ( P = 0.04). We included demographic, clinical, and imaging variables in the univariate analysis and in the subsequent multivariate analysis.Ī total of 204 patients were included in this study. Our aim was to explore the role of ABO blood group in DCI and clinical outcomes after aneurysmal SAH (aSAH).Ī retrospective analysis was made with data collected from patients who presented aSAH at our single- academic center from 2015 to 2018. However, the role of ABO blood type in delayed cerebral ischemia (DCI) onset, clinical progress, and outcome after SAH is to date largely unexplored. In recent years, the role of ABO blood type moved into focus through the discovery of different hemostaseologic properties with importance in many diseases including subarachnoid hemorrhage (SAH). KEYWORDS: ABO blood type, Birth weight, Pregnancy. We postulate that maternal/fetal immune system genes which are directly associated with ABO blood groups could affect pregnant with a resulting birth weight alterations. Birth weeks of all groups were found to be similar with no statistically significant difference Conclusions: Maternal ABO phenotype is associated with low birth weight, while no association was found between blood type and birth week. Pregnant women with type B blood group had significantly lower birth weights compared with type O, A and AB. Results: 500 charts of mothers who had given birth in our hospital were studied. Birth week was also noted for each subject. Adverse pregnancy outcome studied was low birth weight. Methods: Medical data including ABO phenotypes were collected from hospital database and retrospectively reviewed.
The aim of the present study is to determine whether ABO blood group contributes to the adverse pregnancy outcomes like low birth weight. The association between ABO blood group and adverse pregnancy outcomes has not been extensively studied, especially in relation to birth weight. Blood group A patients are at highest risk of DIND following aSAH.īackground: ABO blood group has been recognized as a risk factor for distinct disease states. Blood group A patients had a significantly increased risk of developing DIND, compared with non-blood group A patients (OR, 1.88 ).ĪBO blood type appears to influence aSAH sequelae. The distribution of ABO group or Rhesus status in our cohort did not differ significantly from the general population in the UK. Hospital mortality rate, Glasgow Outcome Score (GOS) - at discharge and 3 months post-ictus, requirement for ventriculoperitoneal shunt insertion, discharge destination and inpatient length of stay were also considered.įour-hundred twelve adult patients admitted with aSAH were included in our analysis.
Clinical outcomes such as initial bleeding, rebleeding, delayed cerebral ischaemia (DIND) and venous thromboembolism were analysed in relation to the size of their association with ABO blood type. Patients were categorised by ABO blood type and by Rhesus status. Retrospective, single-centre study of patients admitted to a neurosurgical department in the UK, with a diagnosis of spontaneous subarachnoid haemorrhage between May 2014 and January 2020. To evaluate the distribution and impact of ABO blood group on the baseline characteristics and clinical outcomes of patients presenting with aneurysmal subarachnoid haemorrhage (aSAH).
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